Article 4

Comparison of Ti-oss® and Bio-oss®​ in New Bone Formation 
on Rat Calvarial Defect in 8 Weeks Period on Rat Calvarial Defect

Jun, Sangho, DDS
Korea University Hospital, Dental Division

Oral and Maxillofacial Department

2014

• Bone Graft Biology

• Biopsy

• Sinus Augmentation

• Vertical Augmentation

• Extraction Like Defect

• Periodontal Defect

• Research & Articles

• Videos

• References

Ti-oss® showed better bone formation than Bio-oss® in 8 weeks period on rat calvarial defect.

6 Rat calvarial defects were made with trephine bur and each 3 defects were filled in with Ti-oss® and Bio-oss®.

8 weeks after, they were sacrificed and tissue slides were made to examine the new bone formation from the defect border. (horizontal section)

Blue color; new cancellous bone                      

Red color; remodeled cortical bone

Ti-oss® made new bone formation to the center of the trephine defect.

Please click on the images for a comfortable view.

#1  Ti-oss®

Bio-oss® made new bone formation to the halfway to the center of the trephine defect.
#5  Bio-oss®